Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep751 | Pituitary and Neuroendocrinology | ECE2020

Evaluation of haemolitic complement activity (ch50) and igg subclasses in adult growth hormone deficiency: Preliminary data

Vergani Edoardo , Bruno Carmine , Basile Umberto , Napodano Cecilia , Piunno Gaia , Stefanile Annunziata , Gulli Francesca , Mancini Antonio

Adult Growth Hormone Deficiency (GHD) is a condition characterized by low grade chronic inflammation; increased levels of free light chains of immunoglobulins have been described; moreover, it shares some features with metabolic syndrome (MetS), including insulin resistance and oxidative stress, but with a different pattern of antioxidant response. Finally, it is known that GH, directly or via IGF-1 activity, influences many aspects of immune response; both humoral and cellula...

ea0056gp128 | Female Reproduction | ECE2018

Low-dose SKA Progesterone and Interleukin-10 modulate the inflammatory pathway in endometriotic cell lines

Mancini Francesca , Milardi Domenico , Carfagna Piero , Grande Giuseppe , Miranda Vincenzo , De Cicco Nardone Alessandra , Ricciardi Domenico , Pontecorvi Alfredo , Marana Riccardo , De Cicco Nardone Fiorenzo

Endometriosis is a chronic gynecological inflammatory disease characterized by the presence of functional endometrial glands and stroma outside of the uterine cavity. It affects 7–10% of women of reproductive age, up to 50% of women with infertility and up to 60% of women with dysmenorrhea. The aim of this pre-clinical study was evaluate the efficacy of low-dose SKA Progesterone (GUNA) and low-dose SKA IL-10 (GUNA) in the modulation of the inflammatory response in endomet...